Friday, February 20, 2015

[Z113.Ebook] Ebook Download The Strange Library, by Haruki Murakami

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The Strange Library, by Haruki Murakami

From internationally acclaimed author Haruki Murakami—a fantastical illustrated short novel about a boy imprisoned in a nightmarish library.
 
Opening the flaps on this unique little book, readers will find themselves immersed in the strange world of best-selling Haruki Murakami's wild imagination. The story of a lonely boy, a mysterious girl, and a tormented sheep man plotting their escape from a nightmarish library, the book is like nothing else Murakami has written. Designed by Chip Kidd and fully illustrated, in full color, throughout, this small format, 96 page volume is a treat for book lovers of all ages.

  • Sales Rank: #24293 in Books
  • Brand: Knopf Publishing Group
  • Published on: 2014-12-02
  • Released on: 2014-12-02
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.39" h x .34" w x 5.52" l, .35 pounds
  • Binding: Paperback
  • 96 pages
Features
  • New In Publisher Shrink Wrap

Amazon.com Review

An Amazon Best Book of the Month, December 2014: What an odd and oddly beautiful little book. A little boy enters a quiet library -- “even more hushed than usual,” we’re told in the opening line -- and is sent to Room 107, where he meets a creepy old librarian who leads him deep into a maze of dark catacombs beneath the library. There, we learn of the librarian’s ghoulish designs and the boy encounters a small man wearing the skin of a sheep and a pretty young girl pushing a teacart, their worlds now “all jumbled together.” Not even fresh-made doughnuts can sweeten the boy’s nightmarish predicament as the librarian’s prisoner. The Strange Library was designed and illustrated by famed book jacket designer (and frequent Murakami collaborator) Chip Kidd, whose moody and mysterious depictions of a child’s (and a parent’s) darkest dream match Murakami’s surreal imagination. It’s hard to discern the message. Maybe something about knowledge being free or the value of libraries. No matter. This is vintage Murakami and, at the same time, something entirely fresh. No one puts animal skins on humans like Murakami. No one would dare. --Neal Thompson

Review
“As if the work of Japanese fiction master Haruki Murakami weren't strangely beautiful by itself, his American publisher has just put out a stand-alone edition of his 2008 novella The Strange Library, in a new trade paperback designed by the legendary Chip Kidd. . . . The story itself, full of characters and images both awfully weird and utterly down to earth, transforms as you read it, becoming a living, nearly talismanic exercise in how to lift yourself out of the realm of the ordinary and allow the sentences to carry you into an alternate universe. . . . The mysterious pleasure of it all is the payoff when you read Murakami. Some scholar may explain it to us all one day, diagram the roots of his work in the Japanese storytelling tradition, in fable and myth, the special effects he imports from American literature. For me, now, I'm just enjoying basking in the heat of this hypnotic short work by a master who is playing a long game.” —Alan Cheuse, NPR

“[A] charming, surreal story. . . . Cleverly designed and illustrated by Chip Kidd. . . . Whether he is writing for adults or children, [Murakami] remains a suspenseful and fantastical storyteller.” —The Washington Post

“It had me enthralled . . . a story of childhood, death and reading, drawn in both words and pictures, like a fairytale, yet there was nothing childish about it. . . . Let the Murakami-mania begin (again).” —Arifa Akbar, The Independent (London)

“Murakami’s wry metaphysical play feels no less diffuse in this concentrated form. His usual fascinations—the instability of identity, the uses of knowledge, the oppression of memory—fade in with just enough time to fade out, offering just enough light to coax you forward, deeper into the dream.” —The Boston Globe
 
“Welcome . . . once again, to Murakamiland: sheep men, waifs, quests, attentiveness to little (odd) things, a labyrinth, a stairway down . . . absurdity and irrationality, the tension between the fantastical and the everyday, real and unreal, sadness and loss, then sudden shifts out of the blue, and plenty of the plain runic. . . . [The Strange Library] plumb[s] the kind of questions that leave us all wishing for more room to breathe: the singular and ever-solitary individual . . . the loss of identity (for better or worse), groping in the dark, self-understanding in an unknowable world, the dignity of idiosyncrasies. . . . The spirit and tone of the writing: As if Murakami is driving down a strange road, not know[ing] what’s to come around the next curve: alert, aware, but as in the dark as the reader. He is, however, a really good driver.” —The Christian Science Monitor
 
“Those who come to Mr. Murakami’s work for the first time will be elated by the clarity and wit of his style as translated by Ted Goossen, and intrigued by his characters and the situations they face. The Strange Library . . .  stays in the mind because of its combination of brutality with flippancy, but mostly for its oddness. . . . In its own odd way it is a fun read.”—Washington Times

“The Strange Library is a subteen’s No Exit. . . . Beautifully designed. . . . Perfect for coffee tables in the gladsome season. . . . Readers looking for a light diversion in a heavily loaded holiday season should enjoy this existential vision.” —The Miami Herald
  
“Japanese master Haruki Murakami's short fantasy tale The Strange Library, designed by Chip Kidd with sublime vintage Japanese graphics, takes readers on a wondrous journey to the mysterious underbelly of a Tokyo library.” —Elle
 
“Striking. . . . [This] dryly funny, concise fable has all the hallmarks of the author’s deadpan magic, along with some Grimm and Lewis Carroll thrown in for good measure. . . . The perfect trip down the rabbit hole.” —The Free Lance-Star (Fredericksburg)
 
“Murakami manages to endow [these] pages with all that we have come to expect from his more leviathan tomes. . . . [Chip Kidd’s illustrations] seem so essential that, having experienced Murakami’s story in this version, one can hardly imagine it in any other form.” —The Japan Times

“Dreamlike. . . . What is immediately clear . . . is just how much thought went into the design and illustrated content. . . . Published by Knopf, the U.S. edition is a Chip Kidd production, and while Kidd’s prolific portfolio demonstrates how comfortable he is working within any and all design idioms, The Strange Library is an in-your-face zoom-in on the faded comics qualities Kidd so often employs when working on Murakami titles. . . . [The illustrations] are what ignite the reader’s thoughts about what the narrator is up against. . . . The designs force the reader to actually read, and read into, the design. . . . Everything that comes to pass in The Strange Library, like in so much of Murakami’s fiction, questions the differences between what is real and what is not, and whether such a distinction even matters. . . . Evocative, atmospheric.” —The Millions

“Can a font be heart-breaking? I didn’t think so, until now. . . . More than anything, I found myself free-associating while reading The Strange Library: Kafka, Dalí, Nabokov, and Poe all came to mind.” —Jon Morris, PopMatters

“Designed by Chip Kidd, nearly every other page contains a beautiful image, often an abstract representation of what is happening to the narrator. This sinister story and gorgeous artwork come together like an unforgettable nightmare. This one has some major gifting potential.” —Bustle

“At once beguiling and disquieting—in short, trademark Murakami—a fast read that sticks in the mind. . . . Murakami loves two things among many: Franz Kafka (think Kafka on the Shore) and secret places (think 1Q84). This latest, brief and terse, combines those two passions. . . . It would take a Terry Gilliam, or perhaps a Kurosawa, to film Murakami’s nightmare properly.” —Kirkus Reviews
 
“This dryly funny, concise fable features all the hallmarks of Murakami's deadpan magic, along with splashes of Lewis Carroll and the brothers Grimm. . . . Full-page designs from Chip Kidd divide the sections, bolstering the book's otherworldliness with images from the text alongside mazelike designs and dizzying close-ups of painted faces.” —Publishers Weekly

About the Author
HARUKI MURAKAMI was born in Kyoto in 1949 and now lives near Tokyo. His work has been translated into more than fifty languages, and the most recent of his many international honors is the Jerusalem Prize, whose previous recipients include J. M. Coetzee, Milan Kundera, and V. S. Naipaul.

Most helpful customer reviews

87 of 91 people found the following review helpful.
A picture book for adults, from Murakami's younger days
By C. E. Stevens
Reading "Strange Library" feels like a trip down memory lane ... or perhaps "down a well" or "into a dark basement" would be the more appropriate analogy, given that this is Murakami we're talking about. Written in 1982, adapted as a illustrated, stand-alone short story in 2005, translated into English in 2014, it is important to remember that this is not "new" Murakami, but rather very early Murakami--to put it into context, the original short story was published at pretty much the same time as "A Wild Sheep Chase," just 3 years after his debut novel "Hear the Wind Sing."

As for the story itself, do not be deceived by the quick pace, young protagonist, the illustrations, and simple vocabulary: this is not a children's story, but rather a "fantasy for adults" as the book cover on the Japanese version states. The elements of magical realism are what you'd expect from entering-his-prime Murakami, the themes of detachment, loss, and coming-of-age (as well as the requisite mysterious, pretty young woman) will be familiar to veteran Murakami readers, and the ever-present menace, oppression, and threat of violence foreshadow the darker parts of some of his later works. The combination of cute pictures and whimsical elements with what really is a pretty heavy storyline heightens the dissonance--and, I would argue, the enjoyment--of this unique work. Despite being a quick read, it is one that sticks with you and flits around the subconscious long after you close the cover for the last time ... like a dream ... or perhaps a nightmare.

37 of 40 people found the following review helpful.
Allegory of grief and loss
By B. Moore
Strange Library is a dark work, powerful in its own terms, yet ultimately quite stark and grim.
The first thing to note is the exquisite design of the book. A Kindle version will not do. It is a beautiful object and is meant to be handled and appreciated for the artistry of presentation. There are all sorts of little things, like, for instance, a notation on the spine of the book that let's one know that one cannot read the book outside the precincts of the library. So, you, the reader, are also inside the strange library.

The voice of this work is vintage early Murakami: Whimsy, laconic humor, a mysterious beautiful girl, a sheepman, labyrinths, and worlds with permeable borders. Critics sometimes note a connection to the French theorist, Lacan, and a theme of ever deferred desire in Murakami. This may be true, but this work is more Heidegger and his notion that all being is "being towards death," for mortality is the overt threat and deep context that suffuses the entire tale with ennui.
For the rest of this, I am going to talk details, so this is a spoiler alert. Don't read further if you do not wish to discover the plot and denouement.

The modern West is secular, superficially optimistic, and more deeply nihilistic. This is my view. We distract ourselves from the ominous and ever present danger of death, which we nonetheless have hidden away as much as possible. Our consumerism is driven by the need for novel spectacle to keep darkness at bay. And yet, we are also still the heirs of Western Christendom. Why this excursus? Because Christianity tells a story of death's defeat. The most fundamental reality is deeply comic, because life has the last word.

So, even a secularist in the West will often bear a trace of religious belief. We like happy endings and we "believe" in them. Thus, Murakami's tale will be unsettling and disappointing, because it subverts hope. Death is victor in this fairly tale for adults.
If one wants a rationalist version that could explain the plot. Here it is. A little boy, thoughtful and sensitive, is living with a sick mother and his pet bird. At a subconscious level, he knows his mother is dying, but he doesn't want to face it. Then one day, his pet bird dies. The death of the bird makes grief and loss existentially real for him. The yawning abyss of loneliness that awaits should his mother die suddenly becomes overwhelmingly real. The little boy hides out in a library for three days. He loses his new shoes. When he returns home, his mother is sweet to him and doesn't berate him, for she is full of unspoken understanding.
The last page of the book is written in tiny print. The boy's voice is reduced to almost nothing. His grief wishes to make tragedy disappear. He announces that his mother has died of a mysterious illness and he is alone. Grim, single m.
In this context, the fabulous tale is an effort to escape what cannot be escaped. That is why the boy's allies disappear and his seemingly successful attempt comes abruptly to nothing. The boy's courteous nature before the menacing old man is a wish that decency and good manners would win out over evil and decay, but it just doesn't. More could be teased out, but this is probably already too prolix.

Bottom line: This is a good, early work, but you might feel cheated. You might feel it's unnecessarily bleak and mean. One might alternatively appreciate the work as a blend of adult insight, ingenious design, and child-like dreaming that embodies an idiosyncratic myth. The darkness at the end may appear a relief from sentimental and too cheaply bought victories.
This reader appreciates the latter possibility, but as a believer in what Peter Leithart calls "deep comedy," I was rueful of the ending. I prefer Murakami when he offers a more comic vision, though I suspect his metaphysical agnosticism more naturally tends in this direction.

1 of 1 people found the following review helpful.
‘“If all they did was lend out knowledge for free, what would the payoff be for them?”
By Reading Bifrost
‘“If all they did was lend out knowledge for free, what would the payoff be for them?”
“But that doesn’t give them the right to saw off the tops of people’s heads and eat their brains. Don’t you think that’s going a bit too far?’”

If you haven’t ever read a story by Murakami before, he’s odd. Very odd. I’m trying my best to review this without giving away any spoilers at all for those who just want to read the story and for those who like to dig for the deeper meanings.

That being said, The Strange Library is a short story presented in a lone book. The book itself is odd, the cover has to be flipped open and has very strange vintage Japanese illustrations to match the story. Everything about the story seems simple and straightforward- not digging deep into characters or plots- adding a richness and dreamlike quality to the story.

But, if you take it to the true Murakami level of reading (we’re talking deep philosophy here) then the reader just might see that the story really revolves around the boy, his pet bird, his mother, and death.

visit blog for original review with details (contains spoiler)

Overall The Strange Library was a fabulously odd short short story wether you’re just looking for a quick read or something you can sink your teeth into. I’d suggest getting a hardcopy instead of an ebook for this one just because the Chip Kidd design does add a lot to the story.

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Wednesday, February 18, 2015

[I224.Ebook] Fee Download Corporate Finance Law: Principles and Policy (Second Edition), by Louise Gullifer, Jennifer Payne

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Corporate Finance Law: Principles and Policy (Second Edition), by Louise Gullifer, Jennifer Payne

The second edition of this acclaimed textbook continues to provide a discussion of key theoretical and policy issues in UK corporate finance law. Fully updated, it reflects developments in the law and the markets in the continuing aftermath of the global financial crisis. One of its distinctive features is that it gives equal coverage to both the equity and debt sides of UK corporate finance law, and seeks, where possible, to compare the two. The topics covered include: an overview of the financing options available to companies * the relationship between debt and equity * the issuance of shares * legal capital * contractual protection for creditors * proprietary protection for creditors * syndicated loans and bond issues * the transfer of debt, including structures which have a similar effect to transfer * public offers of shares * the regulation of the secondary market, including disclosure rules and market abuse regulation * the regulation of debt * takeovers * schemes of arrangement and private equity. Each chapter analyzes the present law critically so as to enable the reader to understand the difficulties, risks, and tensions in this area of law, and the attempts made by the UK's legislature and the courts, as well as the parties involved, to deal with them. The book will be of interest to practitioners, academics, and students engaged in the practice and study of corporate finance law. [Subject: Corporate Law, Finance Law]

  • Sales Rank: #2082264 in Books
  • Published on: 2015-12-14
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.50" h x 1.70" w x 6.70" l, .81 pounds
  • Binding: Paperback
  • 936 pages

Review
Praise for the First Edition

.a treasure trove of information on a number of disparate subjects...The treatment throughout is stimulating and informative (David Marks QC International Company and Commercial Law Review)

About the Author
Louise Gullifer is Professor of Commercial Law and Jennifer Payne is Professor of Corporate Finance Law, both at the University of Oxford.

Most helpful customer reviews

0 of 0 people found the following review helpful.
Five Stars
By yuroj
good

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Thursday, February 12, 2015

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Sunday, February 8, 2015

[N505.Ebook] Fee Download Beyond the Boundary, by Kelvin Long

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Beyond the Boundary, by Kelvin Long

The Initiative for Interstellar Studies is a non-profit organisation dedicated to the pursuit of technologies and the sociological and cultural conditions required for one day achieving interstellar flight. Beyond the Boundary is their first book, featuring 21 chapters from scientists, artists, enthusiasts and journalists on all manner of topics relating to interstellar flight and exploration, including launch vehicles, propulsion systems, pre-cursor missions, exoplanets, SETI, wormholes, warp drive, starship communication and artificial intelligence. For more details about the Initiative for Interstellar Studies, visit www.i4is.org.

  • Published on: 2016-01-12
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.02" h x 1.19" w x 5.98" l, 1.82 pounds
  • Binding: Hardcover
  • 460 pages

Most helpful customer reviews

0 of 0 people found the following review helpful.
Great popular science book on interstellar travel
By Amazon Customer
This book assembles a number chapters on topics related to interstellar travel, written by different authors. The topics stretch from existing interstellar precursor missions such as Voyager and Pioneer to current exoplanet research, artificial intelligence, manned interstellar travel, and the art of interstellar travel. The chapters are easy to read. Complex topics such as neural networks in artificial intelligence are nicely explained. Numerous illustrations are included, although they are black and white.

What I liked most about the book is that it covers at the same time the basic issues of interstellar travel such as the destinations (near-by stars / exoplanets), propulsion systems and at the same time introduces inspiring topics such as ways how artificial intelligence could help us getting to the stars.

Overall, a very nice read as an introduction to interstellar travel covering an astonishing breadth of topics and at the same time provides a lot of food for thought.

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[J917.Ebook] Download Foundations of Game Engine Development, Volume 1: Mathematics, by Eric Lengyel

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Foundations of Game Engine Development, Volume 1: Mathematics, by Eric Lengyel

The first volume of Foundations of Game Engine Development discusses the mathematics needed by engineers who work on games or other types of virtual simulations. The book begins with conventional treatments of topics such as linear algebra, transforms, and geometry. Then, it introduces Grassmann algebra and geometric algebra to provide a much deeper understanding of the subject matter and highlight the places where traditional arithmetic with vectors, matrices, quaternions, etc., isn't quite correct. Includes exercises.

  • Chapter 1: Vectors and Matrices
  • 1.1 Vector Fundamentals
  • 1.2 Basic Vector Operations
  • 1.2.1 Magnitude and Scalar Multiplication
  • 1.2.2 Addition and Subtraction
  • 1.3 Matrix Fundamentals
  • 1.4 Basic Matrix Operations
  • 1.4.1 Addition, Subtraction, and Scalar Multiplication
  • 1.4.2 Matrix Multiplication
  • 1.5 Vector Multiplication
  • 1.5.1 Dot Product
  • 1.5.2 Cross Product
  • 1.5.3 Scalar Triple Product
  • 1.6 Vector Projection
  • 1.7 Matrix Inversion
  • 1.7.1 Identity Matrices
  • 1.7.2 Determinants
  • 1.7.3 Elementary Matrices
  • 1.7.4 Inverse Calculation
  • 1.7.5 Inverses of Small Matrices
  • Chapter 2: Transforms
  • 2.1 Coordinate Spaces
  • 2.1.1 Transformation Matrices
  • 2.1.2 Orthogonal Transforms
  • 2.1.3 Transform Composition
  • 2.2 Rotations
  • 2.2.1 Rotation About a Coordinate Axis
  • 2.2.2 Rotation About an Arbitrary Axis
  • 2.3 Reflections
  • 2.4 Scales
  • 2.5 Skews
  • 2.6 Homogeneous Coordinates
  • 2.7 Quaternions
  • 2.7.1 Quaternion Fundamentals
  • 2.7.2 Rotations With Quaternions
  • Chapter 3: Geometry
  • 3.1 Triangle Meshes
  • 3.2 Normal Vectors
  • 3.2.1 Calculating Normal Vectors
  • 3.2.2 Transforming Normal Vectors
  • 3.3 Lines and Rays
  • 3.3.1 Parametric Lines
  • 3.3.2 Distance Between a Point and a Line
  • 3.3.3 Distance Between Two Lines
  • 3.4 Planes
  • 3.4.1 Implicit Planes
  • 3.4.2 Distance Between a Point and a Plane
  • 3.4.3 Reflection Through a Plane
  • 3.4.4 Intersection of a Line and a Plane
  • 3.4.5 Intersection of Three Planes
  • 3.4.6 Intersection of Two Planes
  • 3.4.7 Transforming Planes
  • 3.5 Pl�cker Coordinates
  • 3.5.1 Implicit Lines
  • 3.5.2 Homogeneous Formulas
  • 3.5.3 Transforming Lines
  • Chapter 4: Advanced Algebra
  • 4.1 Grassmann Algebra
  • 4.1.1 Wedge Product
  • 4.1.2 Bivectors
  • 4.1.3 Trivectors
  • 4.1.4 Algebraic Structure
  • 4.1.5 Complements
  • 4.1.6 Antivectors
  • 4.1.7 Antiwedge Product
  • 4.2 Projective Geometry
  • 4.2.1 Lines
  • 4.2.2 Planes
  • 4.2.3 Join and Meet
  • 4.2.4 Line Crossing
  • 4.2.5 Plane Distance
  • 4.2.6 Summary and Implementation
  • 4.3 Matrix Inverses
  • 4.4 Geometric Algebra
  • 4.4.1 Geometric Product
  • 4.4.2 Vector Division
  • 4.4.3 Rotors
  • 4.5 Conclusion

  • Sales Rank: #327706 in Books
  • Published on: 2016-09-11
  • Original language: English
  • Dimensions: 9.25" h x .47" w x 7.50" l,
  • Binding: Paperback
  • 200 pages

Most helpful customer reviews

0 of 0 people found the following review helpful.
Five Stars
By Nicholas LeFave
A well written reference for the mathematics required for application development using Graphics APIs

3 of 4 people found the following review helpful.
Excellent to revise 3D math concepts
By Amazon Customer
Excellent book! Unlike other books on similar topics, it doesn't just leave you on the basics, it takes you all the way through to the stuff that is actually used.
Looking forward to more volumes in this series.

1 of 2 people found the following review helpful.
Best game development mathematics book
By Amazon Customer
Excellent book on the basics of mathematics applied to computer graphics and game development.
Wonderful print with great images and well taken example. Love it !

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Saturday, February 7, 2015

[B142.Ebook] Ebook Download Flexographic Image Reproduction Specifications and Tolerances 5.1: First 5.1, by Flexographic Technical Association

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FIRST 5.1 is the industry's most comprehensive set of specifications, guidelines and tutorials designed to provide all members of the flexographic supply chain with the technical information they need to produce high quality and consistent print results, pressrun after pressrun. For FTA Member pricing visit http://www.ftastore.com

  • Sales Rank: #1856752 in Books
  • Published on: 2015-09-30
  • Original language: English
  • Number of items: 1
  • Dimensions: 11.00" h x .98" w x 8.50" l, 2.85 pounds
  • Binding: Paperback
  • 414 pages

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Friday, February 6, 2015

[B881.Ebook] Ebook Cellular Signal Processing: An Introduction to the Molecular Mechanisms of Signal Transduction, by Friedrich Marks, Ursula Klingmülle

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Cellular Signal Processing is intended for use in signal transduction courses for undergraduate and graduate students. It offers a unifying view of cell signaling that is based on the concept of protein interactions acting as sophisticated data processing networks that govern intracellular and extracellular communication. The content is guided by three major principles that are central to signal transduction: the protein network, its energy supply, and its evolution. It includes coverage of all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling. It also highlights the clinical aspects of cell signaling in health and disease.

  • Sales Rank: #1278945 in Books
  • Brand: Brand: Garland Science
  • Published on: 2008-11-14
  • Original language: English
  • Number of items: 1
  • Dimensions: 11.25" h x 8.25" w x .75" l, 2.75 pounds
  • Binding: Paperback
  • 656 pages
Features
  • Used Book in Good Condition

Review

"This book would be highly useful to undergraduate students in medical, bioinformatics or biological science that are studying or pursuing research into signal transduction, network or systems biology.� This book would also appeal to graduate students or professionals moving into this field of research, without prior knowledge or experience....each chapter engages the reader and conveys the importance of biological systems and networks adequately, thus challenging the reader to continue viewing their specific focus or field of research in complete isolation."

Immunology News, November 2010

"This book provides comprehensive coverage of signal transduction.� Unlike other texts currently available, a common theme of data processing by cellular machinery runs through this book which makes it stand out favorably against the competition.� Material is up-to-date and covers the areas that are at the forefront of cell signaling research today."
Alexey Veraksa, University of Massachusetts, Boston

"The diversity of appropriate cell cycle topics covered is impressive.� Impressive amount of important information.� Best summary of cell cycle biochemistry in a text."
Bradley J Stith, University of Colorado

"The organization of the proposed book is excellent.� The fundamentals of data processing by protein networks and evolution of this data processing in the first two chapters is the unique feature of the book and sets up the framework of cell signal transduction.� This should allow students to get a firm grip of the overall pictures of cell signalling networks before zooming into the specific topics.� Such chapters are largely missing from other textbooks.� Figures are well executed and informative."
Wei-Jen Tang, Univesrity of Chicago

About the Author

Friedrich Marks, PhD, is Professor of Biochemistry at the University of Heidelberg and Emeritus Department head, German Cancer Research Center. Dr. Marks has been teaching biochemistry, in particular signal transduction, for more than 30 years. His research has focused on the role of signaling reactions in tumor development.

Ursula Klingm�ller, PhD, is a lecturer at the University of Heidelberg and Head of the Systems Biology of Signal Transduction Division, German Cancer Research Center. Dr. Klingm�ller's research focuses on systems biology of signal transduction and dynamic pathway modeling.

Karin M�ller-Decker, PhD, is a lecturer at the University of Heidelberg and Head of the Tumor Models Units, German Cancer Research Center. Dr. M�ller-Decker is conducting pioneering work on eicosanoid signaling in tumor development.

Most helpful customer reviews

11 of 11 people found the following review helpful.
Exceptionally Well Done in Scope and Detail
By Dr. Terrence McGarty
Cellular Signal Processing presents a well-structured and comprehensive discussion of all of the elements in cell signalling. The book provides a superb source of information as well as structure to understand the nuances of many of the cellular signalling mechanisms. It is an excellent desk reference which one can come back to time and again to be used in systems modeling as well as other applications.

It begins with a simple overview of the elements of cell signalling and discusses the reaction dynamics leading to the temporal characteristics of signalling, specifically the simple biochemical switch. Unlike Klipp et al Systems Biology: A Textbook , this book presents a high level description of the signalling rather than developing and demonstrating the specifics of the mathematical model and its actual dynamics. Again using Klipp as a backup would be perfect.

Chapter 2 discusses some of the cell energy considerations and the discussion on protein phosphorylation is exceptionally good. The introduction of protein kinases and their importance in transduction is well placed and sets the stage for later development. Chapter 3 discusses the evolutionary development of cell signalling and this is a good vehicle to demonstrate the development of various specific signalling elements.

Chapter 4 discusses the protein kinases in more detail and the inclusion of many medical applications is exceptionally good. For example the discussion on p 163 regarding the use of aspirin is a nice blend of the practical and the scientific. This type of discussion is diffused throughout the text and makes for enlightening elements.

Chapter 6 is a good presentation of signal transduction and it provides a full description of how the signal paths are activated.

Chapter 9 is a very well done presentation on signals controlling mRNA translation, key to many cancer pathways. For example the discussion on the mTOR pathway, p 337, is quite enlightening as the clinical discussion of diabetes on p 343. Chapter 11 discusses mitogen activation which is essential for understanding the dynamics of cancer pathways. The discussion of NFkB is well done on p 409. This is extended to the application to cancer on p 415. This again is an excellent blending of the science and the application to specific medical uses.

Chapter 12 is on cancer and cell signalling. It focuses on cell cycles and signalling and is an superb complement to Morgan's The Cell Cycle: Principles of Control (Primers in Biology) (Primers in Biology) book. Chapter 13 discusses apoptosis. This is a good complement to the cancer discussion and the cell cycle. Chapter 17 is a short discussion of systems biology. It could have been expanded yet it may have gone beyond the scope of the book.

Overall the book covers all of the signalling pathways and demonstrates with adequate detail the pathways dependencies and allows for an understanding of their dynamics. The book is comprehensive and provides more than adequate reference materials. I have used this book to gain specific details and refresh an understanding or to see an different approach. It is an invaluable addition to any bookshelf.

0 of 0 people found the following review helpful.
Excellent book
By Victor M Baizabal A
Prof. Friedrich Marks and colleages did an outstanding job. The book is well organized, easy to read and understand. It is great that they have included a chapter on energetics for signaling transduction mechanisms. It makes this book not a repetition of what has been written so far. The only thing authors should consider to improve is the artwork, but in no way this fact decreases the quality of the book.

Victor Baizabal, PhD
Professor
Chair of Molecular Immunology and Signal Transduction Laboratory
Universidad Michoacana de San Nicol�s de Hidalgo

0 of 0 people found the following review helpful.
Cell Signal Processing Made Clear
By Kerry Enright
A clear, crisp, comprehensive [at the current state of knowledge] description of cell signal processing. Friedrich Marks steps through each element of signal processing in carefully bounded segments closed with summaries. He does a good job of defining terms to aid clarity.

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